Nitrolingual® Pumpspray is indicated for acute relief of attack or prophylaxis of angina pectoris.

Where is the best place to spray Nitrolingual® Pumpspray?

It should be sprayed onto or under the tongue. Nitrolingual® Pumpspray should not be inhaled.

How many sprays can I use when I am having an angina attack?

At the onset of an angina attack, spray one or two metered sprays onto or under the tongue. No more than three metered sprays are recommended within a 15-minute period. If pain persists, seek prompt medical attention.

What is the ideal position for taking Nitrolingual® Pumpspray?

It is recommended that you use Nitrolingual® Pumpspray for angina treatment while sitting.

Is it normal to have a drop of nitroglycerin lingual spray left on the nozzle after spraying?

Yes. The measuring chamber is designed to give you the proper dose, even though you may notice a drop of liquid left on the nozzle.

How often do I need to prime my Nitrolingual® Pumpspray?

Before using Nitrolingual® Pumpspray for the first time, the pump must be sprayed five times into the air (this is known as priming). The pump should be primed every six weeks to remain ready for use. If the product has not been used for six weeks, a prime of one lingual spray is necessary.

Why shouldn't Nitrolingual® Pumpspray be shaken?

Nitrolingual® Pumpspray does not need to be shaken before use. Shaking the bottle may displace the liquid in the tube.

What happens if the bottle breaks?

The Nitrolingual® Pumpspray bottle is coated in plastic for protection. In the chance that it does break, please contact your pharmacist.

May I use Nitrolingual® Pumpspray to help prevent an angina attack?

Nitrolingual® Pumpspray may be used 5-10 minutes prior to engaging in activities that might provoke an acute angina attack. Be sure to always have a bottle on hand and in a convenient location. Follow your healthcare professional's recommendations regarding activities and exercise.

Important Safety Information:

Nitrolingual® Pumpspray should not be used if you are allergic to nitroglycerin or if you are using medications for erectile dysfunction such as avanafil, sildenafil, vardenafil, or tadalafil. Using Nitrolingual® Pumpspray with these products may cause low blood pressure (hypotension), fainting, or heart attack.

Nitrolingual® Pumpspray should not be used if you have anemia.

Nitrolingual® Pumpspray should not be used in patients with increased intracranial pressure. Talk to your doctor if you had a cerebral hemorrhage or traumatic brain injury before taking Nitrolingual® Pumpspray.

You might develop a tolerance to this drug or to other nitrates and nitrites. Only the smallest number of doses required for effective relief of the acute angina attack should be used.

You should use nitroglycerin with caution in the early days after a heart attack and it may aggravate the angina caused by a condition known as hypertrophic cardiomyopathy. Increased hypotension, mainly when standing upright, may occur even with small doses of nitroglycerin and may result in slow heart beat and increased angina. It should be used with caution if you are dehydrated due to drug therapy or if you have low blood pressure.

Headache is the most reported side effect and may be severe and persistent. Other side effects that have been reported are dizziness, numbness and tingling of the skin, drowsiness, nausea, increased heart rate.

Learn More

Talk to your healthcare provider to see if Nitrolingual® is right for you.

You are encouraged to report negative side effects of prescription drugs to the FDA.

Visit www.fda.gov/medwatch or call 1-800-FDA-1088 FREE

For full prescribing information, click the link below.

Full Prescribing Information