A nitroglycerin spray that's effective, reliable, and ready for patients when they need it.
For patients with angina due to CAD, AHA/ACC/ACP treatment guidelines recommend the use of short-acting nitrates for acute relief and prophylaxis of angina pectoris. (1)
... with angina should receive a prescription for sublingual nitroglycerin and education about its proper use." (1)
... be educated that sublingual nitroglycerin is a short-acting drug so that they will not be reluctant to use it. (1)
74% of patients expressed fear about exercise.
85% of patients agreed that more patients would exercise if they knew their angina medication could be used as a preventive measure before exercise.
Nitrolingual® Pumpspray (nitroglycerin lingual spray) improves patients’ exercise tolerance, while addressing the acute symptoms of angina pectoris. (6)
In a dose-ranging study of patients who had previously experienced a cardiac event,
(1) American Heart Association. ACC/AHA/ACP-ASIM Guidelines for the management of patients with chronic stable angina: Executive summary and recommendations: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Patients With Chronic Stable Angina). Circulation. 1999;99:2829-2848.
(2) Mayo Clinic Staff. Angina. Mayo Clinic website. http://www.mayoclinic.com/health/angina/DS00994/DSECTION=treatments-and-drugs. Accessed October 18, 2011.
(3) Franklin BA, et al. Cardiac rehabilitation and secondary prevention of coronary heart disease: An American Heart Association scientific statement from the Council on Clinical Cardiology and the Council on Nutrition, Physical Activity, and Metabolism, in collaboration with the American Association of Cardiovascular and Pulmonary Rehabilitation. Circulation. 2005;111:369-376.
(4) Thompson PD. Exercise prescription and proscription for patients with coronary artery disease. Circulation. 2005;112:2354-2363.
(5) Data on file at Allegis Pharmaceuticals.
(6) Thadani U, Wittig T. A randomized, double-blind, placebo-controlled, crossover, dose-ranging multicenter study to determine the effect of sublingual nitroglycerin spray on exercise capacity in patients with chronic stable angina. Clinical Medicine Insights; Cardiology. 2012; 6:87-95.
Nitrolingual® Pumpspray is indicated for acute relief of an attack or prophylaxis of angina pectoris due to coronary artery disease.
Nitrolingual® Pumpspray should not be used if you are allergic to nitroglycerin or if you are using medications for erectile dysfunction such as avanafil, sildenafil, vardenafil, or tadalafil. Using Nitrolingual® Pumpspray with these products may cause low blood pressure (hypotension), fainting, or heart attack.
Nitrolingual® Pumpspray should not be used if you have anemia.
Nitrolingual® Pumpspray should not be used in patients with increased intracranial pressure. Talk to your doctor if you had a cerebral hemorrhage or traumatic brain injury before taking Nitrolingual® Pumpspray.
You might develop a tolerance to this drug or to other nitrates and nitrites. Only the smallest number of doses required for effective relief of the acute angina attack should be used.
You should use nitroglycerin with caution in the early days after a heart attack and it may aggravate the angina caused by a condition known as hypertrophic cardiomyopathy. Increased hypotension, mainly when standing upright, may occur even with small doses of nitroglycerin and may result in slow heart beat and increased angina. It should be used with caution if you are dehydrated due to drug therapy or if you have low blood pressure.
Headache is the most reported side effect and may be severe and persistent. Other side effects that have been reported are dizziness, numbness and tingling of the skin, drowsiness, nausea, increased heart rate.
Talk to your healthcare provider to see if Nitrolingual® is right for you.
You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch or call 1-800-FDA-1088 FREE
For full prescribing information, click the link below.